Histopathological Spectrum of Endometrial Biopsy in Women of Reproductive, Perimenopausal and Postmenopausal Age Presenting with Abnormal Uterine Bleeding at Ruhs-Cms Attached Rdbp Jaipuria Hospital, Jaipur

Introduction: Abnormal uterine bleeding is the commonest presenting symptom and major gynecological problem responsible for as many as one-third of all outpatient’s gynecologic visit. Abnormal Uterine Bleeding (AUB) is defined as any bleeding that does not correspond with the frequency, duration or amount of blood flow of a normal menstrual cycle. The various methods of determining the endometrial pathology are dilatation and curettage, fractional curettage, endometrial biopsy and Hysterectomy specimen. The endometrial sampling is chosen to evaluate abnormal uterine bleeding because it has several advantages over other diagnostic methods¹. The histopathological examination of endometrium in perimenopausal and postmenopausal women will pin point the underlying disease and helps in proper management of these patients. Methodology: In the present study 200 cases of endometrial biopsy specimens collected as per inclusion criteria were subjected to the fixation with 10% buffered formalin, grossing, tissue processing and staining with Harris haematoxylin and eosin stain. Microscopic evaluation was done of each specimen along with the clinical data on hand. Results: The present study included endometrial biopsies referred to department of pathology, RUHS College of medical sciences, Jaipur from various outpatient departments of attached hospital. We included a total of 200 cases as per the inclusion and exclusion criteria. The mean age of study group was 41.22±10.85 years. The minimum age was 23 years and maximum age was 73 years. Maximum number of cases were in 3rd decade of life with 86 (43%) cases followed by 4th decade with 52 (26%) cases. Least number of cases was observed in 7h decade with 2 cases (1%). Majority of the patients were in reproductive age group i.e. between 18 - 39 years (56%) followed by perimenopausal age group i.e, 40 - 50 years. (26%).